According to Gazzetta dello Sport, the Naples club believe Senesi would be the perfect heir to Koulibaly.
Physically powerful and technically gifted, the Argentine has been a revelation since joining Feyenoord from San Lorenzo last year.
However, with just 18 days of the market remaining, the chances of Koulibaly staying are growing.
Napoli are ready for Koulibaly’s potential departure though, with a move for 23-year-old Senesi lined up.
Atalanta have already held talks with Feyenoord for the €20m-rated defender.