Wagner, 32, joined Tianjin from Bayern for €5m in January 2019 after a lack of game time for the Bavarians.
The Germany international scored 12 goals in 26 appearances in his first Chinese Super League season.
However, he has now torn up his contract with Tianjin by mutual consent.
Explaining the decision to BILD, Wagner explained the decision was family-related amid the Coronavirus pandemic.
“I had a great 18 months in China and am grateful for the experience that I was able to have,” said Wagner.
“But I have a family at home with four children. In the current circumstances, I am afraid to travel to China and leave them here alone.”
The news of Wagner’s departure from China will alert Bundesliga clubs in need of a forward.
Wagner has been a prolific goalscorer for numerous German clubs including Bayern, Hoffenheim and Darmstadt.
In his eight appearances for Germany, Wagner has found the net five times.